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Incidence of mosaic cell lines in vivo and malsegregation of chromosome 21 in lymphocytes in vitro of trisomy 21 patients: detection by fluorescence in situ hybridization on binucleated lymphocytes

โœ Scribed by Q. Shi; I.-D. Adler; J. Zhang; X. Zhang; X. Shan; R. Martin


Publisher
Springer
Year
2000
Tongue
English
Weight
112 KB
Volume
106
Category
Article
ISSN
0340-6717

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## BACKGROUND. Chromosomal abnormalities in some lymphomas are associated with a poor prognosis. Trisomy 12 and deletions of chromosome 13 have been described in small lymphocytic lymphoma (SLL). To determine whether chromosomal aberrations could be detected by fluorescence in situ hybridization (F