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Incidence of intracranial meningiomas in Nagasaki atomic-bomb survivors

✍ Scribed by Naoki Sadamori; Shobu Shibata; Mariko Mine; Hisaya Miyazaki; Hitoshi Miyake; Masaki Kurihara; Masao Tomonaga; Ichiro Sekine; Yutaka Okumura


Publisher
John Wiley and Sons
Year
1996
Tongue
French
Weight
547 KB
Volume
67
Category
Article
ISSN
0020-7136

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✦ Synopsis


Among the Nagasaki atomic-bomb survivors registered at the Scientific Data Center for Atomic-Bomb Disaster, Nagasaki University School of Medicine, 45 cases of surgically treated intracranial meningiorna were collected from 6 hospitals with departments of neurosurgery in or near Nagasaki City during the period from I973 to 1992. All 45 patients were over 40 years of age at the time of diagnosis. Subsequently, the 45 cases were statistically analyzed in relationship to the estimated distance from the hypocenter by age, gender, intracranial location, histology and latent period. The analysis showed a high correlation between incidence of meningiomas and distance from the hypocenter. The incidence among Nagasaki atomic-bomb survivors over 40 years of age, especially in those proximally exposed, appears to be increasing, in inverse proportion to the exposure distance, since I98 I, 36 years after the explosion of


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T h e present study demonstrates a n increased prevalence of malignant lymphoma and multiple myeloma in survivors of the atomic bomb in Hiroshima exposed to 100 rad or more; a similar relationship is not evident in Nagasaki. This apparent discrepancy is tentatively attributed to known physical diffe