Incidence of HPV in primary and metastatic squamous cell carcinomas of the aerodigestive tract: implications for the establishment of clonal relationships
โ Scribed by C Will; C Schewe; I Petersen
- Book ID
- 108780018
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 62 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0309-0167
No coin nor oath required. For personal study only.
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BACKGROUND. Chemoprevention and cessation of smoking and alcohol may prevent development of multiple tumors (MTs) in the aerodigestive tract if new MTs arise independently, but they are of no benefit if MTs are due to migration of an already transformed clone of tumor cells. This issue was addressed
Thirty-five previously untreated patients with stage IV squamous cell carcinoma of the upper aerodigestive tract with advanced neck disease (mass > 3 cm) but with primary lesions thought to be locally controllable with radiotherapy were selected between 1972 and 1988 for treatment by neck dissection