Purpose:
The first purpose of this study was to determine the incidence of postoperative nausea and/or vomiting (ponv) 0-48 h after anesthesia at a japanese cancer center. the second purpose of this study was to collect information on ponv risk factors, independently, in the categories of patient-related, anesthesia-related, and surgery-related factors.
Methods:
The frequency of nausea and vomiting was prospectively investigated from 0 to 48 h after anesthesia in 1645 patients (11-94 years of age) at a single medical institution. the occurrence of nausea and vomiting and the use of antiemetics were recorded up to 48 h after anesthesia. patient-related, anesthesia-related, and surgery-related factors were also recorded and submitted to multiple logistic regression analysis to determine the relationship of these factors to nausea and vomiting.
Results:
The incidences of nausea and vomiting from 0 to 24 h after anesthesia were 40 and 22 %, respectively. the incidences 24-48 h after anesthesia were 10 and 3 %, respectively. female sex, previous history of ponv, prolonged anesthesia, and remifentanil use during surgery were identified as risk factors for both nausea and vomiting. the use of a volatile anesthetic, use of fentanyl during surgery, postoperative use of opioids, nonsmoking status, and drinking alcohol on 4 or fewer days per week were identified as risk factors for nausea alone.
Conclusion:
The incidence of and risk factors for ponv at a japanese cancer center according to this study are comparable to those reported elsewhere.