Incidence and survival rates of children and young adults with osteogenic sarcoma
β Scribed by David M. Homa; Maryfran R. Sowers; Ann G. Schwartz
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 662 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0008-543X
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High-dose methotrexate (HDMTX), adriamy-overall and disease-free survival rates were 70% cin (ADR), and cisplatinum (CDDP) are effective and 59%, respectively. Factors which favorably agents in the treatment of osteogenic sarcoma influenced prognosis on univariate analysis were (OS). Individual pati
## Abstract ## BACKGROUND Highβdose methotrexate (HDMTX) is used frequently in combination regimens that include nephrotoxic chemotherapy. The authors evaluated the impact of factors such as age and prior nephrotoxic agents on MTX pharmacokinetics in children and young adults with osteosarcoma and