Inbred strain variation in lung function
β Scribed by Claudia Reinhard; Gunter Eder; Helmut Fuchs; Axel Ziesenis; Joachim Heyder; Holger Schulz
- Book ID
- 106014939
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 401 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0938-8990
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## Abstract Lung tumor susceptibility in inbred mouse strains is caused by the susceptibility allele at the pulmonary adenoma susceptibility 1 (__Pas1__^__s__^) locus. However, after urethane treatment, most strains carrying the __Pas1__^__s__^ allele show an intermediate (1β4 tumors/mouse) instead
## Abstract Among overtly identical mice of an inbred strain, some are relatively susceptible and some relatively resistant to sarcomagenesis by large concentrations of 3βmethylβcholanthrene (MCA) (Prehn, 1975a). Spleen cells from mice, subsequently shown to be relatively susceptible, conveyed a re