Inappropriate reporting and interpretation of subgroups in the AML-BFM 93 study
β Scribed by Wheatley, K; Hills, RK
- Book ID
- 110055032
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 81 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0887-6924
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The prognostic significance of Auer rods in predicting response rate and remission duration was investigated in 257 patients of the two West German acute myelogenous leukemia (AML) studies BFM-78 and -83. Auer rods were found in 129 children (50%) in the initial bone marrow smear. The incidence was
## Abstract ## BACKGROUND. Data on the impact of age in acute myeloid leukemia (AML) patients <30 years treated in pediatric and adult trials are scarce. ## METHODS. In all, 891 patients <18 years were treated in the pediatric trials AMLβBFM 93/98 and 290 adolescents and young adults (>16 to <30