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Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart

✍ Scribed by András Farkas; Aasim Qureshi; Michael J Curtis

Book ID
110004520
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
306 KB
Volume
128
Category
Article
ISSN
0007-1188

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✍ Ronelle Mouton; Barbara Huisamen; Amanda Lochner 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 748 KB

In this study the mass of polyphosphoinositides as well as the turnover of [3H]inositol phospholipids and [3H]inositol phosphates during ischaemia and short periods of reperfusion were studied in the isolated perfused rat heart. Since the phosphoinositides located within the sarcolemma are precursor