Arginine facilitates inactivation of env
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Hisashi Yamasaki; Kazuko Tsujimoto; A. Hajime Koyama; Daisuke Ejima; Tsutomu Ara
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Article
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2008
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John Wiley and Sons
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English
โ 127 KB
Virus inactivation is a key step for the purification of pharmaceutical proteins derived from recombinant mammalian expression systems and conventionally done using low pH-treatment, which is often harmful to the proteins to be purified. This is particularly true for antibodies, because immunoglobul