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Inactivation of tissue inhibitor of metalloproteinases-1 (TIMP-1) by Porphyromonas gingivalis

✍ Scribed by Daniel Grenier; Denis Mayrand

Book ID
117517055
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
170 KB
Volume
203
Category
Article
ISSN
0378-1097

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Tissue inhibitor of metalloproteinases-1
Tissue inhibitor of metalloproteinases-1 (TIMP-1) inhibits tumor growth and angiogenesis in the TIMP-1 transgenic mouse model
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## Abstract The tissue inhibitor of matrix metalloproteinases‐1 (TIMP‐1) has been recognized as a multifunctional protein. The role of TIMPs in cancer remains the subject of conflicting reports with an antitumor activity or a tumor growth stimulation activity by several mechanisms. The aim of our s