## Abstract The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known whether the Y chromosome harbors such
Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases
β Scribed by Teng, Y; Ren, M Q; Cheney, R; Sharma, S; Cowell, J K
- Book ID
- 110000636
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 993 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract 3,3β²βDiindolylmethane (DIM) has been studied for its putative antiβcancer properties, especially against prostate cancer; however, its exact mechanism of action remains unclear. We recently provided preliminary data suggesting downβregulation of uPA during BβDIM (a clinically active DIM
## Background: In previous reports, we used microcell fusion-mediated chromosomal transfer to introduce normal human chromosomes into highly metastatic rat prostatic cancer cells to map the location of tumor and metastasis suppressor genes. the gene for prostate-specific antigen as well as several