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Inactivation of spermidine N1-acetyltransferase with alkaline phosphatase

✍ Scribed by Isao Matsui; Shuzo Otani; Masaharu Kamei; Seiji Morisawa

Book ID
115914138
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
258 KB
Volume
150
Category
Article
ISSN
0014-5793

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✍ Woonyoung Choi; Lynsey Proctor; Qianghua Xia; Yumei Feng; Eugene W. Gerner; Paul πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 240 KB

## Abstract Spermidine/spermine __N__(1)‐acetyltransferase (SSAT) is a key enzyme in polyamine catabolism. We recently reported that the combination of __N__^1^, __N__^11^‐diethylnorspermine (DENSPM) and 5‐fluorouracil (5‐FU) synergistically induces SSAT expression, depletes polyamine levels and ca