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Inactivation of p53 results in high rates of homologous recombination

✍ Scribed by Mekeel, Kristin L; Tang, Wei; Kachnic, Lisa A; Luo, Chen-Mei; DeFrank, Jeffrey S; Powell, Simon N

Book ID
110060752
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
662 KB
Volume
14
Category
Article
ISSN
0950-9232

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High levels of recombination induced by
High levels of recombination induced by homologous P elements in Drosophila melanogaster
✍ Sved, John A. ;Blackman, Leila M. ;Stuart Gilchrist, A. ;Engels, William R. πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 763 KB

P element transposons in Drosophila melanogaster are capable of mobilizing incomplete P elements elsewhere in the genome, and of inducing recombination. This recombination is usually only of the order of 1% or less. We show that two P elements, located at exactly homologous sites, induce levels of r