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Inactivation of p38 kinase delays the onset of senescence in rabbit articuilar chondrocytes

✍ Scribed by Seokwon Kang; Munsu Jung; Chul-Woo Kim; Deug Y. Shin


Book ID
113775793
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
315 KB
Volume
126
Category
Article
ISSN
0047-6374

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## Abstract This study addresses mechanisms by which interleukin‐1Ξ² (IL‐1Ξ²) regulates human chondrocyte apoptosis induced by a combination of the anti‐CD95 antibody CH‐11 and the proteasome inhibitor (PSI). The effect of IL‐1Ξ² on apoptosis varied among tissue samples. IL‐1Ξ² either enhanced (16/22 s