✦ LIBER ✦

Inactivation of p16 by methylation in human lung adenocarcinoma

✍ Scribed by Divine, Kevin K.; Gilland, Frank D.; Stidley, Christine A.; Bocklage, Therese J.; Schwartz, Ann; Cook, Dennis L.; Belinsky, Steven A.

Book ID: 109830388
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 40 KB
Volume: 27
Category: Article
ISSN: 1061-4036
DOI: 10.1038/87058

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Frequent inactivation of the p16 gene in

Frequent inactivation of the p16 gene in human pituitary tumors by gene methylation

✍ Michael Woloschak; Aiqin Yu; Kalmon D. Post 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 2 views

Rodent models of pituitary tumorigenesis have implicated the retinoblastoma (Rb) pathway in the development of pituitary tumors. Previously, we reported that loss of p16 expression rather than loss of Rb occurs in most human pituitary adenomas. This alteration in these tumors is not associated with

p16 inactivation in small-sized lung ade

p16 inactivation in small-sized lung adenocarcinoma: Its association with poor prognosis

✍ Beniyo Kawabuchi; Sachiko Moriyama; Mitsugu Hironaka; Takeshi Fujii; Morio Koike 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 105 KB

p16, an inhibitor of cell cycle machinery, is frequently inactivated in non-small cell carcinoma of the lung (NSCCL). To clarify the significance of p16 inactivation in the progression of lung adenocarcinoma, we immunohistochemically evaluated p16 protein status and Rb, p53 and cyclin D1 expression

Inactivation of the p16 gene by hypermet

Inactivation of the p16 gene by hypermethylation and loss of heterozygosity in adenocarcinoma of the lung

✍ Hirokazu Awaya; Yukio Takeshima; Vishwa Jeet Amatya; Osamu Furonaka; Kohei Tagaw 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 59 KB

Inactivation of p16INK4a expression in m

Inactivation of p16INK4a expression in malignant mesothelioma by methylation

✍ Wong, Long; Zhou, Joan; Anderson, Daniel; Kratzke, Robert A 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 170 KB

Prevalence of human papillomavirus 16/18

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma

✍ Reika Iwakawa; Takashi Kohno; Masato Enari; Tohru Kiyono; Jun Yokota 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB

DNA methylation and expression of p16INK

DNA methylation and expression of p16INK4A gene in pulmonary adenocarcinoma and anthracosis in background lung

✍ Mei Hou; Yukio Morishita; Tatsuo Iljima; Yukinori Inadome; Kentaro Mase; Yuichi 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 203 KB 👁 2 views

The p16 (CDKN2/MTS-1/INK4A) tumor-suppressor gene is frequently inactivated by DNA methylation in lung carcinomas. To clarify whether background anthracosis may play a role in DNA methylation and inactivation of the p16 gene, we examined DNA methylation of the p16-promoter region by methylation-spec