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Inactivation of Nitric Oxide Synthase Isoforms by Diaminoguanidine andNG-Amino-L-arginine

✍ Scribed by Donald J. Wolff; Andrew Lubeskie


Book ID
115565872
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
141 KB
Volume
325
Category
Article
ISSN
0003-9861

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Three derivatives of the mechanism-based inhibitor \(N^{\mathrm{G}}\)-allyl-L-arginine, designed to eliminate the effect of charge on the \(\alpha\)-functional groups, were synthesized and tested as inhibitors of purified bovine brain nitric oxide synthase. The inhibitory properties of \(N^{\mathrm{