𝔖 Bobbio Scriptorium
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Inactivation of human sodium channels and the effect of tocainide

✍ Scribed by B. Fakler; J. P. Ruppersberg; W. Spittelmeister; R. Rüdel


Book ID
110567831
Publisher
Springer
Year
1990
Tongue
English
Weight
825 KB
Volume
415
Category
Article
ISSN
0031-6768

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Stereoselective interaction of tocainide
✍ D. Tricarico; B. Fakler; W. Spittelmeister; J. P. Ruppersberg; R. Stützel; C. Fr 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 868 KB

The effects of both enantiomers of tocainide and of some of its chiral analogs on the inactivation of the sodium current in human myoballs were investigated with the whole-cell recording technique. Structure and electron densities of the applied compounds were calculated and compared to the results.