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Inactivation of hepatocyte Protein Kinase C by carbon tetrachloride: Involvement of drug's metabolic activation and prooxidant effect

✍ Scribed by M.A. Pronzato; C. Domenicotti; F. Biasi; E. Chiarpotto; D. Cottalasso; P. Viotti; E. Melloni; U.M. Marinari; G. Poli


Book ID
115762995
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
514 KB
Volume
171
Category
Article
ISSN
0006-291X

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Role of diacylglycerol (DAG) in hormonal
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The role of diacylglycerol (DAG) in hormonal induction of S phase was investigated in primary cultures of rat hepatocytes. In this model, several agonists that bind to G protein-coupled receptors act as comitogens when added to the cells soon after plating (i.e., in Go/early Gl phase), while the cel