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Inactivation of GABA receptors by phenoxybenzamine: Effects on GABA-stimulated benzodiazepine binding in the central nervous system

โœ Scribed by Roger W.J. Smokcum


Book ID
115877257
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
399 KB
Volume
86
Category
Article
ISSN
0014-2999

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A 32 year old patient with refractory complex partial seizures was treated with vigabatrin for 3.5 years. Before starting treatment and at 42 months. lumbar punctures were done and the CSF analyzed for amino acids including GABA. Although the patient experienced a 50% seizure reduction, he underwent