Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549
β Scribed by Sithanandam, Gunamani; Fornwald, Laura W; Fields, Janet; Anderson, Lucy M
- Book ID
- 110069441
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 572 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Active oxygen species are generated in cells during pathophysiologic conditions such as inflammation and postischemic reperfusion. If oxygen radical scavengers are added before reperfusion, then the magnitude of injury is reduced. We investigated whether free radicals generated following exposure to
## Abstract Pyrogallol (PG) is a polyphenol compound and has been known to be an O generator. We evaluated the effects of PG on the growth of human pulmonary A549 cells in relation to the cell cycle and apoptosis. Treatment with 50 or 100 ΞΌM PG significantly inhibited the cell growth of A549 for 72
## Abstract HMGβCoA reductase catalyzes the synthesis of mevalonate, a crucial intermediate in the biosynthesis of cholesterol and nonβsterol isoprenoid compounds essential for cell growth. The HMGβCoA reductase activity of the A549 tumor cell line is higher than that of normal human fibroblasts. T
## Abstract To map tumor suppressor genes for lung adenocarcinomas, we introduced normal human chromosomes 3, 7, and 11 into the A549 tumor cell line by microcellβmediated chromosome transfer to test which chromosomes had the ability to suppress tumorigenicity. These human chromosomes, which contai