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Inactivation of Enzymes by Therapeutic Concentrations of Aspirin and Salicylate

✍ Scribed by GRISOLIA, S.; MENDELSON, JUDITH; DIEDERICH, DENNIS

Book ID
109667841
Publisher
Nature Publishing Group
Year
1969
Tongue
English
Weight
228 KB
Volume
223
Category
Article
ISSN
0028-0836

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Rats received the equivalent of 100, 250, 500, or 700 mg/kg of 14C-aspirin orally as a suspension or as a solution of a buffered, effervescent, aspirin-containing product. Animals in each dose group were sacrificed at time intervals ranging from 0.5 to 24 hr after dosing. The 14C content of whole bl