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Inactivation of creatine kinase induced by dopa and dopamine in the presence of ferrylmyoglobin

✍ Scribed by Toshiaki Miura; Sanae Muraoka; Yukio Fujimoto


Book ID
114009798
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
166 KB
Volume
123
Category
Article
ISSN
0009-2797

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Dopamine has been implicated as a potential mediating factor in a variety of neurodegenerative disorders. Dopamine can be oxidized to form a reactive dopamine quinone that can covalently modify cellular macromolecules including protein and DNA. This oxidation can be enhanced through various enzymes