Inactivation of the catalytic subunit of
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Shahriar Mobashery; Michael Doughty; E. T. Kaiser
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Article
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1990
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Wiley (John Wiley & Sons)
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English
โ 610 KB
A peptide affinity inactivator, Ac-Leu-Arg-Arg-Ala-(BrAc)Om-Leu-Gly, was used as a tool t o probe for active site residues in the catalytic subunit of bovine CAMP-dependent protein kinase. The peptide inactivated the catalytic subunit in an active site-directed and monophasic manner with a first-ord