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Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura

โœ Scribed by H. B. FEYS; N. VANDEPUTTE; R. PALLA; F. PEYVANDI; K. PEERLINCK; H. DECKMYN; H. R. LIJNEN; K. VANHOORELBEKE


Book ID
109154399
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
382 KB
Volume
8
Category
Article
ISSN
1538-7933

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## Abstract Thrombotic thrombocytopenic purpura (TTP) is a rare but severe disorder characterized by hemolytic anemia, thrombocytopenia, fever, renal failure, and neurologic manifestations. Plasma exchange is the most effective treatment for this condition reducing mortality from 90% in untreated p