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Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

โœ Scribed by Li, Meng; Zhao, Hong; Zhang, Xiaosong; Wood, Laura D; Anders, Robert A; Choti, Michael A; Pawlik, Timothy M; Daniel, Hubert D; Kannangai, Rajesh; Offerhaus, G Johan A; Velculescu, Victor E; Wang, Linfang; Zhou, Shibin; Vogelstein, Bert; Hruban, Ralph H; Papadopoulos, Nick; Cai, Jianqiang; Torbenson, Michael S; Kinzler, Kenneth W

Book ID
124099966
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
184 KB
Volume
43
Category
Article
ISSN
1061-4036

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Somatic mutations in the chromatin remod
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
โœ Siรขn Jones; Meng Li; D. Williams Parsons; Xiaosong Zhang; Jelle Wesseling; Petra ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 180 KB

Mutations in the chromatin remodeling gene __ARID1A__ have recently been identified in the majority of ovarian clear cell carcinomas (OCCCs). To determine the prevalence of mutations in other tumor types, we evaluated 759 malignant neoplasms including those of the pancreas, breast, colon, stomach, l