THEOPHYLLINE CONTROLLED-RELEASE FORMULAT
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Zhiling Yu; Joseph B. Schwartz; Edwin T. Sugita
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Article
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1996
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John Wiley and Sons
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English
โ 647 KB
Four experimental controlled-release oral solid dosage formulations were developed and the in vitro dissolution characteristics of theophylline from these formulations were studied in USP apparatus I. Pharmacokinetic evaluation of these formulations was carried out in eight beagle dogs under fasting