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In vivoeffects of anticonvulsant drugs on nerve terminal (synaptosomal) GABA levels in 11 brain regions of the rat

✍ Scribed by W. Löscher; M. Vetter; G. Böhme; Gisela Stoltenburg-Didinger

Publisher
Springer
Year
1985
Tongue
English
Weight
540 KB
Volume
63
Category
Article
ISSN
1435-1463

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The effects of y-aminobutyric acid (GABA) on the spontaneous release of [3H1-norepinephrine (r3H]-NE) were investigated by means of superfused synaptosomes prepared from different areas of the rat brain and prelabeled with t3H]-NE. GABA increased in a concentration-dependent way (1-300 pM) the relea