In vivo validation of MR pulse pressure measurement in an aortic flow model: Preliminary results

✍ Scribed by Steven N. Urchuk; Stephen E. Fremes; Donald B. Plewes

• Book ID: 102956184
• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 944 KB
• Volume: 38
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.1910380209

✦ Synopsis

Abstract

MR imaging experiments were conducted to investigate the feasibility of estimating vascular pulse pressure waveforms from measurements of blood flow rates and vessel cross‐sectional area. Blood flow waveforms were measured in the aorta's of three 25–30‐kg pigs at multiple imaging sections using phase‐contrast velocity imaging. Estimates of pulse pressure were derived from these data by evaluating a model characterizing the relationship between pressure, flow, and the cross‐sectional area of a vessel segment. Comparisons between the MR‐derived estimates of pressure and those obtained from a micromanometer pressure catheter indicate that accurate measurements (mean error ± SD = 8.2 ± 3.4, n = 6) can be obtained using conventional velocity imaging techniques. Optimization of the method will require the application of rapid imaging techniques and the development of strategies for obtaining a more localized measurement. With these improvements, our results suggest that MR‐based measurement of pulse pressure and related elastic parameters is feasible.