𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

✍ Scribed by Zhao, M; Kiyoi, H; Yamamoto, Y; Ito, M; Towatari, M; Ômura, S; Kitamura, T; Ueda, R; Saito, H; Naoe, T

Book ID
110054462
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
122 KB
Volume
14
Category
Article
ISSN
0887-6924

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Apoptotic effect of PP2 a Src tyrosine k
Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia
✍ Michael Lee; Ji-Young Kim; Woo Suk Koh 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 340 KB

## Abstract Src is a non‐receptor protein tyrosine kinase that transduces signals regulating cell growth and differentiation. We report here that activation of signaling pathway after blockade of tyrosine phosphorylation by PP2 (4‐amino‐5‐(4‐chloro‐phenyl)‐7‐(__t__‐butyl)pyrazolo[3,4‐__d__]pyrimidi

Treatment of Philadelphia-chromosome-pos
Treatment of Philadelphia-chromosome-positive human leukemia in scid mouse model with herbimycin A, bcr-abl tyrosine kinase activity inhibitor
✍ Yoshio Honma; Yoshinobu Matsuo; Yasuhide Hayashi; Satoshi Omura 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 731 KB

The molecular basis of the Philadelphia chromosome (Ph') is a structurally altered c-abl (bcr-abl) gene which encodes an abnormally large protein with protein tyrosine kinase activity. Herbimycin A, which effectively reduced intracellular phosphorylation by bcr-abl tyrosine kinase, preferentially in