## Abstract ## Purpose: To investigate the transport of Gd‐DTPA^2−^ in different layers of femoral knee cartilage in vivo. ## Materials and Methods: T~1~ measurements (1.5 Tesla) were performed in femoral knee cartilage of 23 healthy volunteers. The weight‐bearing central cartilage was analyzed
In vivo transport of Gd-DTPA2-into human meniscus and cartilage assessed with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC)
✍ Scribed by Ulf Sigurdsson,Carl Siversson,Eveliina Lammentausta…
- Book ID
- 126375089
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 515 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1471-2474
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The macromolecular structure and mechanical properties of articular cartilage are interrelated and known to vary topographically in the human knee joint. To investigate the potential of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T1, and T2 mapping to elucidate these differences, full-th
## Abstract Quantitative magnetic resonance imaging (MRI) techniques have been developed for noninvasive assessment of the structure of articular cartilage. T~2~ relaxation time is sensitive to the integrity and orientation of the collagen network, while T~1~ relaxation time in presence of Gd‐DTPA^