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In vivo STUDIES ON AN ANTAGONIST OF PARATHYROID HORMONE [Nle-8, Nle-18, Tyr-34]bPTH-(3–34)AMIDE

✍ Scribed by DAVID A. GRAY; Late JOHN A. PARSONS; JOHN T. POTTS Jr.; MICHAEL ROSENBLATT; RALPH W. STEVENSON

Book ID
117957805
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
632 KB
Volume
76
Category
Article
ISSN
0007-1188

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Evaluation in vivo of a potent parathyro
Evaluation in vivo of a potent parathyroid hormone antagonist: [Nle8,18, D-Trp12, Tyr34]bPTH(7–34)NH2
✍ Rivka Dresner-Pollak; Qui-Ming Yang; Vered Behar; Chizu Nakamoto; Dr. Michael Ch 📂 Article 📅 2009 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 462 KB

In an effort to design and select potent parathyroid hormone (PTH) antagonists suitable for clinical utility, a PTH analog was evaluated in vivo in an animal model to assess its properties in preparation for human studies. The previously described PTH antagonist, [Nles. '8,Ty84] bPTH(7-34)NH2, which