In Vivo Spectroscopy

✍ Scribed by Lawrence J. Berliner (ed.), Jacques Reuben (ed.)

Publisher: Springer
Year: 1992
Tongue: English
Leaves: 345
Series: Biological Magnetic Resonance 11
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

In vivo nuclear magnetic and electron spin resonance spectroscopy is concerned, inter alia, with the noninvasive observation of metabolic changes in living systems, including animals and humans. Typically, the physiologi cal (or pathological) state of an organ or tissue is monitored. This multi faceted approach was developed during the 1980s. It is still a research technique, but will undoubtedly become a clinical tool. We are proud to present this volume (the eleventh of our series) in which some of the pioneers in this area summarize their contributions and review related literature. Bolinger and Lenkinski describe a variety of localization methods suitable for clinical applications of NMR spectroscopy. Schleich, Caines, and Rydzewski summarize their contributions to approaches involving off-resonance rotating frame relaxation and critically compare these with other NMR techniques that may yield similar information. Chang and James outline their approach and share their experience with the technical aspects 1 31 of H and P NMR spectroscopy and spatially localized spectroscopy in studies of brain ischemia. Sodium plays an important role in living systems, a key aspect being the large gradient between intra- and extracellular concentrations of sodium that is maintained by a variety of transport mechanisms. Miller and Elgavish give us a comprehensive review of an important research tool in this 23 area- Na NMR spectroscopy as aided by shift reagents.

✦ Table of Contents

Front Matter....Pages i-xiii
Localization in Clinical NMR Spectroscopy....Pages 1-53
Off-Resonance Rotating Frame Spin—Lattice Relaxation....Pages 55-134
NMR Methods in Studies of Brain Ischemia....Pages 135-158
Shift-Reagent-Aided 23 Na NMR Spectroscopy in Cellular, Tissue, and Whole-Organ Systems....Pages 159-240
In Vivo 19 F NMR....Pages 241-276
In Vivo 2 H NMR Studies of Cellular Metabolism....Pages 277-306
Some Applications of ESR to in Vivo Animal Studies and EPR Imaging....Pages 307-319
Back Matter....Pages 321-334

✦ Subjects

Biochemistry, general;Biotechnology;Analytical Chemistry;Biophysics and Biological Physics

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