In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model
β Scribed by Hanazono, Y; Nagashima, T; Takatoku, M; Shibata, H; Ageyama, N; Asano, T; Ueda, Y; Dunbar, C E; Kume, A; Terao, K
- Book ID
- 110039093
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 218 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0969-7128
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## Abstract ## Background __In vivo__ expansion of geneβmodified cells would be a promising approach in the field of hematopoietic stem cell gene therapy. To this end, we previously developed a selective amplifier gene (SAG), a chimeric gene encoding the granulocyte colonyβstimulating factor (GβCS