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In vivo REPAIR OF CYTOSINE HYDRATES IN DNA OF CULTURED HUMAN LYMPHOBLASTS

✍ Scribed by Randi B. Weiss; Patricia E. Gallagher

Book ID
114896717
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
794 KB
Volume
58
Category
Article
ISSN
0031-8655

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## Abstract The cytotoxic effect of 1‐β‐D‐arabinofuranosyl cytosine (araC) depends on the intracellular phosphorylation into its active compound araCTP, on the degree of degradation of araCTP and on the incorporation of araCTP into DNA. Deoxycytidine triphosphate (dCTP) inhibits the phosphorylation