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In vivo relevance of the interplay between IL-6 and C-SRC in the regulation of osteoblast function. Involvement of the IGF-1/IGFBPS axis

✍ Scribed by B. Peruzzi; A. Cappariello; N. Rucci; F. De Benedetti; A. Teti


Book ID
116323210
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
57 KB
Volume
47
Category
Article
ISSN
8756-3282

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## Abstract Insulin‐like growth factor binding protein (IGFBP)‐6 has been reported to inhibit differentiation of myoblasts and osteoblasts. In the current study, we explored the mechanisms underlying IGFBP‐6 effects on osteoblast differentiation. During MC3T3‐E1 osteoblast differentiation, we found