𝔖 Bobbio Scriptorium
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In vivo reconstitution of ricin-like activity from its A and B chain subunits

✍ Scribed by William Cushley; Michael J. Muirhead; Fred Silva; Joyce Greathouse; Thomas Tucker; Jonathan W. Uhr; Ellen S. Vitetta


Book ID
119005951
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
779 KB
Volume
22
Category
Article
ISSN
0041-0101

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Ricin A chain-containing immunotoxins (IT-As) specific for the human &ell antigen, CD22, were prepared from 4 monoclonal antibodies (MAbs) or their Fab' fragments: RFB4, HD6, UV22-I and UV22-2. The ITS were tested for their ability to kill cells from the Burkitt lymphoma line, Daudi, the pre-6cell l