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In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA

โœ Scribed by Steven R Schwarze; Steven F Dowdy


Book ID
117341964
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
76 KB
Volume
21
Category
Article
ISSN
0165-6147

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In Vivo Protein Transduction: Delivery o
โœ Schwarze, S. R. ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› American Association for the Advancement of Scienc ๐ŸŒ English โš– 749 KB

Delivery of therapeutic proteins into tissues and across the blood-brain barrier is severely limited by the size and biochemical properties of the proteins. Here it is shown that intraperitoneal injection of the 120-kilodalton ฮฒ-galactosidase protein, fused to the protein transduction domain from th