✦ LIBER ✦

In Vivo Properties of an In Situ Forming Gel for Parenteral Delivery of Macromolecular Drugs

✍ Scribed by Rajashree Joshi; Vikram Arora; John P. Desjardins; Dennis Robinson; Kenneth J. Himmelstein; Patrick L. Iversen

Book ID: 110308255
Publisher: Springer US
Year: 1998
Tongue: English
Weight: 845 KB
Volume: 15
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1011979505697

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

First report on the efficacy of l-alanin

First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs

✍ François Plourde; Aude Motulsky; Anne-Claude Couffin-Hoarau; Didier Hoarau; Huy 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 202 KB

Biocompatibility of an injectable in sit

Biocompatibility of an injectable in situ forming depot for peptide delivery

✍ Karin Schoenhammer; Julie Boisclair; Helmut Schuetz; Holger Petersen; Achim Goep 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 291 KB

In-situ self-assembling protein polymer

In-situ self-assembling protein polymer gel systems for administration, delivery, and release of drugs

✍ J Cappello; J.W Crissman; M Crissman; F.A Ferrari; G Textor; O Wallis; J.R Whitl 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 292 KB

In situ SAXRD study of sol–gel induced w

In situ SAXRD study of sol–gel induced well-ordered mesoporous bioglasses for drug delivery

✍ Y. F. Zhao; S. C. J. Loo; Y. Z. Chen; F. Y. C. Boey; J. Ma 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 836 KB

## Abstract In this work, two systems of mesoporous bioglasses (MBGs) were sol–gel derived using block copolymer pluronic F127 and P123, respectively, as templates. A two‐dimensional hexagonal (P6mm) mesoporous structure was obtained for the two systems, with __d__‐spacing in (100) reflection of 8.

Acute toxicity evaluation of biodegradab

Acute toxicity evaluation of biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PEG-PCL-PEG hydrogel

✍ Chang Yang Gong; Qin Jie Wu; Peng Wei Dong; Shuai Shi; Shao Zhi Fu; Gang Guo; Hu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 885 KB

## Abstract In this work, a biodegradable poly(ethylene glycol)‐poly(ε‐caprolactone)‐poly (ethylene glycol) (PEG‐PCL‐PEG, PECE) triblock copolymer was successfully synthesized. The aqueous solution of such PECE copolymer displayed special sol–gel–sol transition as temperature increase, which is a f

Development and in vivo evaluation of an

Development and in vivo evaluation of an oral drug delivery system for paclitaxel

✍ Javed Iqbal; Federica Sarti; Glen Perera; Andreas Bernkop-Schnürch 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 221 KB

The aim of the present study was to investigate the effect of poly(acrylic acid)-cysteine (PAA-cysteine) exhibiting a molecular mass of 100 and 250 kDa and reduced glutathione (GSH) on the absorption of the P-glycoprotein (P-gp) and cytochrome P450 (CYP450) substrate paclitaxel in vitro and in vivo.