A new potential antihypertensive drug, irindalone (Lu 21 -098;( +)-(1 R,3S)-1-[2-[4-[3-(pf luoropheny1)-1 -indanyl]-1 -piperazinyl]ethyl]-2-imidazolidinone), has been characterized by a series of in vitro methods. lrindalone competitively inhibits peripheral and central serotonin;! (5-HT2) receptors
✦ LIBER ✦
In vivo pharmacology of irindalone, a 5-HT2 receptor antagonist with predominant peripheral effects
✍ Scribed by Jørn Arnt; Klaus P. Bøgesø; Vita Boeck; Anne V. Christensen; Nils Dragsted; John Hyttel; Torben Skarsfeldt
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 756 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0272-4391
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