✦ LIBER ✦

In vivo pharmacokinetics using MRS

✍ Scribed by Markus Rudin; Nicolau Beckmann; André Sauter

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 13 KB
Volume: 12
Category: Article
ISSN: 0952-3480
DOI: 10.1002/(sici)1099-1492(199910)12:6<404::aid-nbm607>3.0.co;2-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ifosfamide pharmacokinetics and hepatobi

Ifosfamide pharmacokinetics and hepatobiliary uptake in vivo investigated using single- and double-resonance 31P MRS

✍ Laura Mancini; Geoffrey S. Payne; Andrzej S.K. Dzik-Jurasz; Martin O. Leach 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 397 KB

## Abstract MRS has considerable potential for the measurement of drug pharmacokinetics in vivo. In this study single‐ and double‐resonance ^31^P MRS was used to investigate the biodistribution, pharmacokinetics, and metabolism of ifosfamide following administration of 500 mg/kg ifosfamide in guine

Studies of metabolic compartmentation an

Studies of metabolic compartmentation and glucose transport using in vivo MRS

✍ Douglas L. Rothman 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

## Abstract Organs consist of several types of cells with specialized functions. This cellular localization of function is often referred to as compartmentation. Due to the intrinsic low sensitivity of MR methods it is generally not possible __in vivo__ to obtain images or spectra of single cells.

Dynamic in vivo oxymetry using overhause

Dynamic in vivo oxymetry using overhauser enhanced MR imaging

✍ Klaes Golman; J. Stefan Petersson; Jan-Henrik Ardenkjær-Larsen; Ib Leunbach; Lar 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 602 KB

Reproducibility of 1H-MRS in vivo

✍ William M. Brooks; Seth D. Friedman; Christine A. Stidley 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 75 KB

The current study sought to investigate the reproducibility of a quantitative spectroscopic examination, using rigorous positioning guidelines and automated spectral fitting for measuring the cerebral metabolites N-acetylaspartate (NAA), creatine (Cre), choline (Cho), and myo-inositol (ml). Ten subj

In vivo pharmacokinetics of [14C]-etanid

In vivo pharmacokinetics of [14C]-etanidazole

✍ Alberto Breccia; Enrico Gattavecchia; Giorgio Feroci; Adamo Fini; Luciano Busutt 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 355 KB

## Abstract Etanidazole, like other nitroaromatic radio sensitizers, displays its biological activity mostly through two molecular groups: the nitro group and the side‐chain attached to the nitrogen in the imidazole ring in position 1. To monitor the behaviour of the two moieties in vivo, labelled

Parameter estimation for in vivo magneti

Parameter estimation for in vivo magnetic resonance spectroscopy (mrs) using simulated annealing

✍ K. Sekihara; N. Ohyama 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB 👁 1 views

## Abstract A method for estimating the spectral parameters from a noisy FID is proposed. The method uses a priori information concerning the lower and upper limits between which such parameters' values can exist. Computer simulation results show that, using the proposed method, values of the spect