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In vivo pharmacokinetics of aldose reductase inhibitors: 3-fluoro-3-deoxy-D-glucose NMR studies in rat brains

โœ Scribed by Ingrid L. Kwee; Tsutomu Nakada

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
290 KB
Volume
2
Category
Article
ISSN
0952-3480

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โœ Ingrid L. Kwee; Tsutomu Nakada; Nobuyuki Suzuki ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 284 KB

31P and 3-fluoro-3-deoxy-D-glucose (3-FDG) 19F nuclear magnetic resonance (NMR) spectroscopic investigations were performed on aged rat brain in vivo. Phosphodiester (PDE) was found to be significantly higher (p less than 0.05) in aged brain (18 months, n = 10) than adult controls (6 months, n = 10)