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In vivo performance of parenteral theophylline-loaded polyisobutylcyanoacrylate nanoparticles in rats

โœ Scribed by Mahasen A. Radwan; Iman Y. Zaghloul; Zinat H. Aly


Book ID
114302781
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
60 KB
Volume
8
Category
Article
ISSN
0928-0987

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## Abstract Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the bloodโ€brain barrier, they are mostly inaccessible to traditional chemotherapy. We have recently shown that doxorubicin bound to polysorbateโ€coated nanoparticles crossed the intact bloodโ€brain