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In vivo neurochemical monitoring by microdialysis and capillary separations

✍ Scribed by Robert T Kennedy; Christopher J Watson; William E Haskins; David H Powell; Robert E Strecker


Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
167 KB
Volume
6
Category
Article
ISSN
1367-5931

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✦ Synopsis


Microdialysis is valuable for studying the neurochemical changes underlying behavior. Recent advances include the application of the high-sensitivity methods of capillary electrophoresis and capillary liquid chromatography with mass spectrometry to dialysate analysis. These methods have improved temporal resolution, spatial resolution, multi-analyte capability and potential for compound discovery.


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