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In vivo modulation of intracellular cAMP and cell growth of a lymphatic tumour in mice by cholera toxin

✍ Scribed by J. Holmgren; S. Lange; L. Lindholm; Christina Lönnroth; I. Lönnroth

Book ID
119415094
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
665 KB
Volume
108
Category
Article
ISSN
0014-4827

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Cholera toxin (which increases intracellular cAMP levels) significantly (p less than 0.05) increased the growth of MCF-7, T47-D and Hs578T human breast carcinoma cells in vitro. The effect of cholera toxin on growth of MCF-7 and T47-D cells was more pronounced in the presence of 17 beta-estradiol (p