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In vivo micronucleus test with flow cytometry after acute and chronic exposures of rats to chemicals

✍ Scribed by Zoryana Cammerer; Azeddine Elhajouji; Willi Suter


Book ID
116759200
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
349 KB
Volume
626
Category
Article
ISSN
1383-5718

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The genotoxic and cytotoxic effects of etoposide (VP-16), a topoisomerase II inhibitor, on male rat spermatogenic cells were studied by analysing induction of micronuclei during meiosis. Micronuclei (MN) were scored in early spermatids after different time intervals corresponding to exposure of diff