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In vivo metabolism of nasally instilled dihydrosafrole [1-(3,4-methylenedioxyphenyl)propane] in dogs and monkeys

โœ Scribed by Joanna Petridou-Fischer; Sandra L. Whaley; Alan R. Dahl


Book ID
113137021
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
679 KB
Volume
64
Category
Article
ISSN
0009-2797

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The pharmacokinetics and metabolism of Uxepams', a new minor tranquillizer, have been investigated in rats [2], dogs and man. For the experiments in rats [2] separation of metabolites of 2-14C-uxepam was achieved by thin-layer chromatography. In the experiments on dogs and man, Extrelut microcolumn