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In vivo measurement of 32P in the brain of a freely moving rat

✍ Scribed by Dr. A. Mayevsky; D. Samuel; S. S. Friedland; J. H. Ewins

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 865 KB
Volume: 1
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490010309

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A new method for measuring the uptake of materials labeled with radioactive phosphorus (^32^P) in the brain of a freely moving rat is described. The rat of uptake in the brain of a single animal of ^32^P‐labeled phosphate was compared to the uptake rate in the animal's blood or liver. A comparison was made between the uptake following an intravenous (IV) or an intraperitonel (IP) injection. The effect of convulsions caused by injections of metrazol on the kinetics of ^32^P uptake in the brain is described.

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