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In vivo labelling of biotinylated monoclonal antibodies by radioactive avidin: A strategy to increase tumor radiolocalization

✍ Scribed by Giovanni Paganelli; Pietro Riva; Guido Deleide; Alberto Clivio; Francesca Chiolerio; Gian Alfredo Scassellati; Massimo Malcovati; Antonio G. Siccardi

Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
396 KB
Volume
41
Category
Article
ISSN
0020-7136

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## Background: Several strategies have been explored to accelerate monoclonal antibody (mab) conjugate clearance without affecting intratumoral uptake. one of the most promising is extracorporeal immunoadsorption (ecia), in which excess radiolabeled mab circulating in blood is removed. ## Methods: