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In vivo interconversion of 7β-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress

✍ Scribed by Hanna Larsson; Ylva Böttiger; Luigi Iuliano; Ulf Diczfalusy

Book ID
113630335
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
389 KB
Volume
43
Category
Article
ISSN
0891-5849

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## Abstract The oxysterol 7beta‐hydroxycholesterol (7β‐OH) has been shown to induce apoptosis in a number of cell lines. Though not fully elucidated, the mechanism through which this oxysterol induces cell death is thought to involve the generation of an oxidative stress leading to perturbation of