Measuring dopamine transporter occupancy
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Joanna S. Fowler; Nora D. Volkow; Jean Logan; S. John Gatley; Naomi Pappas; Payt
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Article
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1998
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John Wiley and Sons
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English
β 108 KB
Several recent neuroimaging studies in humans and in monkeys using different radiotracers have reported widely differing values of dopamine transporter (DAT) occupancy by doses of cocaine which are perceived as reinforcing by humans. Here we tested the hypothesis that the measurement of DAT occupanc